Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity: Cell Reports Role of Glutathione in Cancer: From Mechanisms to Therapies Human cancer associated fibroblasts enhance glutathione levels and antagonize drug induced prostate cancer cell death Cell Death & Disease