Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Equilibrium solubility, Hansen solubility parameter, dissolution thermodynamics, transfer property and preferential solvation of zonisamide in aqueous binary mixtures of ethanol, acetonitrile, isopropanol and N,N dimethylformamide ScienceDirect Effect of ethanol on the solubilization of hydrophobic molecules by sodium caseinate ScienceDirect DIHEXA Research Capsules Peptide Tech