Heightened innate immunity may trigger chronic inflammation, fatigue and post exertional malaise in ME CFS npj Metabolic Health and Disease Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Frontiers Myalgic Encephalomyelitis Chronic Fatigue Syndrome: the biology of a neglected disease Polyphenols as possible alternative agents in chronic fatigue: a review Phytochemistry Reviews Springer Nature Link