Diverse avenues of research support the transmethylation theory of psychosis: implications for neuroprotection First episode psychosis was marked by elevated medial prefrontal glutamate levels compared with chronic schizophrenia and controls, with higher glutamate associated with lower verbal and visual JAMA Psychiatry Potential Roles of Redox Dysregulation in the Development of Schizophrenia Biological Psychiatry Glutamate and Schizophrenia: From Theory to Treatment Implications Psychiatric Times