What is Glutathione & why is it so important ? OptimOZ.com.au Full article: Glutathione as a mediator of cartilage oxidative stress resistance and resilience during aging and osteoarthritis The ingredient nobody's talking about but should be. Glutathione is your body's ultimate defender against oxidative stress, and most people have never heard of it. Ours has no artificial colors, Sulfur metabolism under stress: Oxidized glutathione inhibits methionine biosynthesis by destabilizing the enzyme cystathionine < em> synthase