My Dog Ate ZYN Pouches? Concern, Solutions, and Safety One of our customers has had first hand experience of this recently. One cigarette butt can contain enough nicotine to poison a dog. Especially puppies and smaller breeds. What can happen Reggie's owner rushed him to the vets after he ate a bottle of e cigarette liquid. Sadly, the vet explains that nicotine is very toxic to dogs and can even be fatal. Channel 5 Facebook Today is 4 20 Here's what to do if you suspect that your dog has ingested marijuana.